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diagnosis differential rheumatology msk hematology pain approach testing autoimmune bloodcell brucellosis classification clinical cll criteria disease erythematosus gap globulin instability
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
rheumatic fever • Chronic ... Lyme), reactive arthritis ... hepatitis, herpes • Chronic ... SLE, psoriatic arthritis ... rheumatology #approach #workup
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Iron deficiency anemia ... , Chronic disease ... myeloma Rouleaux: Chronic ... Multiple myeloma, Chronic ... hematology #microscopy #atlas
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
• Inflammatory arthritis ... Noninflammatory arthritis ... with rheumatoid arthritis ... : • Acute or chronic ... rheumatology #approach #workup
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Approach to Joint ... , erythema and WBC ... acute/subacute/chronic ... • How many joints ... Caused By: - Chronic
Diagnosing Brucellosis Epidemiological Exposures - Endemic Regions - Clinical Micro Lab Technicians - Animal/Vaccine Exposure: Vets, Slaughterhouse workers, hunters - Unpasteurized
Osteoarticular (Sacroiliac joint ... Diagnostic Tests: - CBC ... + Chemistry: Anemia ... Diagnosis #Criteria #Workup
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... Screening Tests for Chronic ... Complete blood count (CBC ... #laboratory #workup
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Lymphocytosis on CBC ... • Neutropenia, anemia ... leukemia #CLL #Chronic ... Leukemia #diagnosis #workup
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
: • Joint pain ... arthropathy • 90% joints ... lymphopenia, low PLT • Anemia ... titers > 1:80 • CBC ... with Lupus: • Chronic
Chronic distal radiocubital instability. The function of this joint is the rotation of the forearm or pronosupination,
Chronic distal radiocubital ... function of this joint ... and synchronous work ... proximal radio-ulnar joints ... wrist #Wrist #msk #orthopedics
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 Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... and often causes arthritis ... Glomerulonephritis, arthritis ... vesicular eruption - Joints ... Lab Tests: • CBC
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