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diagnosis hematology differential oncology algorithm leukemia lymphocytic management rheumatology testing arthritis blood bloodcell causes cell classification disease erythematosus gap globulin
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC) Morphology ... Burr Cell RBC (Echinocyte ... Bite Cell RBC: G6PD ... Unstable hemoglobin disorders ... hematology #microscopy #atlas
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
- CD7, CD3 Chronic ... - Abnormal morphology ... Pelger-Huet, Macrocytic anemia ... • Lymphoid (CLL ... bcr-able (+) ↑ WBC
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... RBC) Morphology ... Atlas • Microcytic ... coagulopathy (DIC) #RBC ... #Morphology #Atlas
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Mean corpuscular (cell ... Red cell distribution ... (BM) ablative disorders ... Algorithm #Diagnosis #Workup
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Consider sickle cell ... other reproducible morphologic ... membrane disorder ... Diagnosis #Algorithm #workup
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Lymphocytosis on CBC ... lymphoproliferative disorders ... • Neutropenia, anemia ... Leukemia #diagnosis #workup
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Thrombocytopenia and Platelet Disorders ... Diagnosis and Workup ... changes), high MCV anemia ... not required in all ... Diagnosis #Causes #Workup
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... leukemia in adults • Disorder ... 5) Symptoms of anemia ... #Chronic #Lymphocytic
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Marrow Failure • Chronic ... Neutropenia • Platelet Disorders ... Workup: • Complete
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Workup ... platelets - WBC
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