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diagnosis differential hematology management infectiousdiseases blood cardiology causes endocarditis fever glomerular nephrology nephrotic product reactions agglutinin algorithm calculation classification cold
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... inclusions - If infection ... #Anemia #Differential ... Diagnosis #Algorithm #workup ... #hematology #testing
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... anemia • Cold ... Positive Coombs testing ... Blood smear - RBC ... #hemolytic #anemia
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
approximately how long ... transform into a RBC ... Chronic kidney disease ... (e.g. cancer, infection ... RBC defects (e.g
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... polymicrobial infection ... Lung abscess ... Lung Abscess - Clinical ... , anemia • Sputum
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
concentrations in: RBCs ... anemia, PNH, immune ... Prosthetic valves Lung ... Pneumonia • Other lung ... • Toxins • Infection
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Crossmatch - involves testing ... Related Acute Lung ... • Infection - ... Infection occurs ... false negatives on testing
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
- M. abscessus ... chelonae • M abscessus ... fortuitum, M. abscessus ... haemophilum • Tropical setting ... Bone Marrow - Anemia
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
• Abscess, bacteremia ... schistosomiasis • Pyemia ... with profound hemolysis ... Brucellosis • Liver or lung ... abscess • Sub-acute
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... procedures - Infection ... smear, HIV/HCV testing ... PT, aPTT(liver disease ... changes), high MCV anemia
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Infectious: • Pre-existing ... devices (CIED) Non-Infectious ... verrucous) • Lung ... Hypercoagulable (APLAS ... Leukocytosis, anemia
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