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diagnosis management differential algorithm treatment clinical cardiology rheumatology pharmacology causes hematology neurology workup pediatrics peds deficiency nephrology pulmonary table anemia
Autoimmune Gastritis - Pathophysiology Anti-ParietaI Cell, CD4+ T Cells, Autoantibodies -> x Parietal Cells, x HCL, x
CD4+ T Cells, Autoantibodies ... Pathophysiology #b12
Etiologies of Vitamin B12 Deficiency • Inadequate intake - Rare but seen in very strict vegans
Etiologies of Vitamin B12 ... dissociated vitamin B12 ... develop vitamin B12 ... with decreased B12 ... parietal cells by autoantibodies
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
Vitamin B12 (Cobalamin ... Etiology: • Vit B12 ... small intestine), autoantibodies ... who don't take B12 ... - Low Vit B12
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
to 50X ULN • Autoantibodies ... to 50X ULN • Autoantibodies ... : >50X ULN • Autoantibodies ... to 10x ULN • Autoantibodies
Systemic Sclerosis Associated Autoantibodies Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Sclerosis Associated Autoantibodies ... Systemic #Sclerosis #Autoantibodies
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in ... RheumOnePagers #Autoantibodies
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
• Thiamine B1 ... • Riboflavin B2 ... gestation • Vitamin B12
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Autoantibodies and ... Goodpasture's syndrome #Autoantibodies
Hypoglycemia Differential Diagnosis and Workup Algorithm Firstly check if it is true (Whipple's triad). After that, check labs
ketone bodies, autoantibodies
Diagnosing Vitamin B12 and/or Folate Deficiency It turns out that simply measuring serum levels of B12 or
Diagnosing Vitamin B12 ... serum levels of B12 ... with low normal B12 ... people with low B12 ... accumulate in B12
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