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hematology differential macrocytosis management mcv workup aafp classification cobalamin deficiency elevatedmcv fatigue folicacid homocysteine ibd microcytic nutrition thrombocytopenia vitamin vitaminb12
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
Algorithm for the ... evaluation of macrocytic ... red blood cell; MMA ... #Diagnosis #Macrocytosis ... #Macrocytic #Anemia
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... - Differential Diagnosis ... Algorithm Normal ... Increased Requirement (e.g ... #Algorithm #Causes
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... Infections Macrocytic ... Megaloblastic: Folate ... deficiency, B12 ... aciduria, Drugs (e.g
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... 14.5% suggests wide ... (EPO), iron or B12 ... of substrate (e.g ... #Algorithm #Diagnosis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... Megakaryopoiesis • Aplastic Anemia ... Megakaryopoiesis • B12 ... #Algorithm #Causes
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Chronic Disease (e.g ... (>100 fL) • B12 ... Deficiency • Folate ... #Algorithm #Causes
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
Crohn's > UC Anemia ... • Supplement folate ... (B12, MMA) for ... /other causes • ... #diagnosis #management
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... : • Worsening macrocytic ... total body stores Evaluation ... - Elevated MMA ... consider other diagnosis
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