594 results
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Differential Diagnosis Algorithm ... Involvement - B-cell ... or λ), Smudge Cells ... - B-cell ... Differential #Diagnosis #Algorithm
Diffuse large B cell lymphoma (DLBCL) - Management and Treatment Algorithm

By Matthew Ho, MD PhD @MatthewHoMD

#Diffuse
Diffuse large B ... cell lymphoma (DLBCL ... and Treatment Algorithm ... Diffuse #large #Bcell ... Management #Treatment #Algorithm
B/T Cell Development
This is a work in progress describing the maturation of B & T cells
B/T Cell Development ... maturation of B ... & T cells in a lymph ... #lymph node #b-cell ... #t-cell
Cellular and humoral immune responses of the adaptive immune system. Activated T cells accomplish cellular immune
responses, and B ... antigen activates B ... to the B-cell receptor ... paths, one using B ... Millions of different B
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
lymphocytes/Mature B ... smear: Smudge cells ... or basket cells ... indicate disease • B ... cell surface molecules
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... predominant (LP) tumour B ... pattern of spread, B ... ~10% - B-Cell ... #differential #algorithm
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
then stimulate B ... recognized by B ... fragment bind B ... complex and enhance B ... blood -> Memory B
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
Airway epithelial cells ... promote dendritic cell ... activate naive CD4 T cells ... These T cells then ... induce B-cell class
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Lymphocytes - T or B ... 75% of ALL is of B-cell ... marrow • Mature B-cell ... : Granulocytic cells ... Accumulation of Mature B
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Natural Killer Cells ... • Humoral: (B ... : (T cell response ... Increased helper cell ... and cytotoxic cell