582 results
B/T Cell Development
This is a work in progress describing the maturation of B & T cells
B/T Cell Development ... maturation of B ... & T cells in a lymph ... #lymph node #b-cell ... #t-cell
Cellular and humoral immune responses of the adaptive immune system. Activated T cells accomplish cellular immune
responses, and B ... antigen activates B ... to the B-cell receptor ... paths, one using B ... Millions of different B
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
lymphocytes/Mature B ... cells can infiltrate ... indicate disease • B ... cell surface molecules ... AIHA • Pure red cell
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Involvement - B-cell ... CD10 - T-cell ... or λ), Smudge Cells ... - B-cell ... Thrombocytosis - T-cell
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
then stimulate B ... recognized by B ... fragment bind B ... complex and enhance B ... blood -> Memory B
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... Framework Knee Effusion ... - Hepatitis B, ... sarcoma - Giant cell ... therapy - Sickle cell
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
Airway epithelial cells ... induce B-cell class ... TH2 cells also migrate ... eosinophils, mast cells ... submucosal mast cells
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Lymphocytes - T or B ... 75% of ALL is of B-cell ... marrow • Mature B-cell ... involvement • T-cell ... Accumulation of Mature B
HHV8/KSHV-reIated diseases: From Cellular Proliferation to Hyperinflammation
Kaposi sarcoma (KS):
 • Target organs: Ubiquitous (cutaneous and mucosal
splenomegaly, effusion ... plasmablasts from pre-GC B ... Monotype Primary effusion ... , B symptoms • ... differentiated B
Diffuse large B cell lymphoma (DLBCL) - Management and Treatment Algorithm

By Matthew Ho, MD PhD @MatthewHoMD

#Diffuse
Diffuse large B ... cell lymphoma (DLBCL ... Diffuse #large #Bcell