30 results
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
- Iron deficiency ... anemia - Anemia ... chronic kidney disease ... - Vitamin B12 ... #hematology #diagnosis
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (<80 fL) • Iron ... Poisoning • Anemia ... Marrow Failure • Anemia ... (>100 fL) • B12
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Differential Diagnosis Algorithm ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional ... deficiency: • B12 ... Differential #Diagnosis #Algorithm
Causes of Iron Deficiency
 • Inadequate Intake: Vegetarian/vegan diet, Malnutrition
 • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Loss (without anaemia ... (IBD, cancer) ... #Iron #Deficiency ... diagnosis #causes #nutrition
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
to Anemia - Differential ... inflammation) • Iron ... Sideroblastic anemia ... ACD, Aplastic anemia ... MatthewHoMD #Anemia
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Deficiency • B12 ... Deficiency • Aplastic Anemia ... • Anemia of Chronic ... Non-lmmune #Anemia
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
deficiency anemia ... anemia (sometimes ... Sideroblastic anemia ... Macrocytic RBC: Vitamin B12 ... differential #diagnosis #hematology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
deficiency • Fanconi’s anemia ... telomeropathy Cancer ... Antibody-mediated hemolysis Nutritional ... consumption • Vitamin B12 ... Differential #Diagnosis #Hematology
Causes of Iron Deficiency
 • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... : Gl lesions / cancer ... : IBD, Chronic disease ... differential #diagnosis #anemia ... #nutrition
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Hypoproliferative Macrocytic Anemia ... Hypothyroid • Liver Disease ... #Macrocytic #Anemia ... differential #diagnosis #algorithm ... #hematology #workup