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diagnosis differential hematology deficiency pancytopenia approach classification cobalamin disease elevatedmcv ileal iron macrocytic macrocytosis management mds mentzerindex myelodysplasia myelodysplastic neutropenia
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... Drugs, H pylori, Celiac ... Iron metabolism disorders ... differential #diagnosis #anemia ... #nutrition
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Causes of Neutropenia ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional ... deficiency: • B12 ... #Causes #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... • Pernicious Anemia ... • Small Bowel Disorder ... • Pernicious Anemia ... #Macrocytic #Anemia
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
Disease - Diagnosis Algorithm ... Iron-deficiency anemia ... without discernable cause ... Disease #Diagnosis #Algorithm ... #gastroenterology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Deficiency • B12 ... Deficiency • Aplastic Anemia ... • Anemia of Chronic ... Non-lmmune #Anemia
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Differential Diagnosis Algorithm ... • Rheumatic disorders ... • Celiac disease ... Iron deficiency anemia
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... autoantibodies (pernicious anemia ... Worsening macrocytic anemia ... wt loss • If anemia ... - CBC, PBS - anemia
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... Anemia is described ... hemoglobin of less than 12 ... that involves disorders ... These causes could
Ileal Pouch Disorders - Differential Diagnosis • Surgical/Mechanical: Anastomotic leak, Pelvic sepsis, Sinus, Fistula, Strictures, Efferent
Ileal Pouch Disorders ... Systemic/Metabolic: Anemia ... Bone loss, Vit D/B12 ... , Renal stone, Celiac ... Diagnosis #surgery #gastroenterology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
blood cell count (anemia ... • Anemia • Aplastic ... Anemia • Bone ... Megaloblastic Anemia ... Myelophthisic Anemia
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