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differential hematology causes mcv workup approach classification cobalamin deficiency disorders elevatedmcv gluten ileal macrocytosis management microcytic morphologic nutrition pouch surgery
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... Diagnosis Framework ... Normocytic ( ... Folate deficiency, B12 ... Non-megaloblastic: Liver disease
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Diagnostic Framework ... 80 - 96 fL - "Normocytic ... chronic kidney disease ... MCV - >96fL - "Macrocytic ... Megaloblastic: Vitamin B12
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... (up to 100) = normocytic ... (EPO), iron or B12 ... #Algorithm #Diagnosis ... #Macrocytic
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Algorithm Normal ... • Drugs Oval Macrocytes ... #Macrocytic ... #Algorithm #Causes
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Hypoproliferative Macrocytic ... Anemia • 812 ... Hypothyroid • Liver Disease ... #Anemia #differential ... #diagnosis #algorithm
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
Disease - Diagnosis ... Algorithm Celiac ... anemia unresponsive ... #Disease #Diagnosis ... #Algorithm #gastroenterology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Algorithm Blood ... Acute Bleed - Normocytic ... Deficiency • B12 ... Disease • Marrow
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
: • Worsening macrocytic ... related to IBD, celiac ... disease, other ... consider other diagnosis ... Cobalamin #Deficiency #diagnosis
Celiac Disease Testing Algorithm INDICATIONS FOR TESTING: Nonspecific symptoms (iron-deficiency anemia, failure to thrive, fever, skin
Celiac Disease Testing ... Algorithm INDICATIONS ... iron-deficiency anemia ... #Algorithm #diagnosis ... #gastroenterology
Ileal Pouch Disorders - Differential Diagnosis • Surgical/Mechanical: Anastomotic leak, Pelvic sepsis, Sinus, Fistula, Strictures, Efferent
- Differential Diagnosis ... Systemic/Metabolic: Anemia ... Bone loss, Vit D/B12 ... , Renal stone, Celiac ... #surgery #gastroenterology
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