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diagnosis management oncology hematology syndromes differentiation emergencies hemeonc immune inflammatory iris mds myelodysplasia myelodysplastic oncologic prs reconstitution renal
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... initiation • Differential ... Renal Failure Treatment
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager ... mononeuritis multiplex WORKUP ... coagulopathy) • CBC w differential ... #differential # ... diagnosis #management #treatment
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Nutritional: vitamin B12 ... factor (GCSF) treatments ... Workup: • Complete ... blood count with differential
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... treat - Calcium > 12 ... (~20 %) and APL ... renal failure, pulmonary
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... • Parvovirus B19 ... Leishmaniasis Differential ... #Inflammatory #Syndrome ... #Differential #
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