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diagnosis causes hematology algorithm cobalamin elevation low mcv pancytopenia vitaminb12 workup acidosis anosmia approach ascorbicacid atlas atrophicglossitis bariatric bloodcell bypass
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
and Vitamin Deficiency ... • Thiamine B1 ... B12 - Anaemia, ... #Deficiency #differential ... signs #symptoms #nutrition
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Pancytopenia - Differential ... • Fanconi’s anemia ... Antibody-mediated hemolysis Nutritional ... consumption • Vitamin ... B12 • Folate deficiency
Micronutrient Deficiencies After Gastric Bypass Fat-Soluble Vitamins: • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
Folate - Macrocytic anemia ... • Vitamin B12 ... - Macrocytic anemia ... #nutrition #table ... #differential #
Causes of Vitamin B12 Deficiency - Cobalamin Decreased Intake Pancreas: Insufficiency Intestine: SIBO, Celiac disease, IBD, Lymphoma, Amyloidosis, Resection,
Causes of Vitamin ... B12 Deficiency ... Stomach: Pernicious anemia ... #B12 #Deficiency ... #Cobalamin #differential
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Algorithm - Iron deficiency ... kidney disease - Vitamin ... B12 and/or folate ... deficiency - ... hematology #diagnosis #differential
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... (>100 fL) • B12 ... Deficiency • ... #MCV #Classification ... #Differential #
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Pancytopenia - Differential ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional ... deficiency: • ... B12/folate/combined
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Microcytic" • Iron deficiency ... Megaloblastic: Vitamin ... B12 deficiency, ... Folate deficiency ... morphologic #mcv #differential
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... Polyphenol / tannins, ↓ Vitamin ... #Causes #differential ... #diagnosis #anemia ... #nutrition
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... • B12/Folate ... Deficiency • Aplastic ... #Classification ... #Approach #Differential
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