14 results
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Corpuscular Volume (MCV ... ) - Differential ... Myelodysplastic Syndromes ... #Macrocytosis #elevatedMCV ... #Differential #
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential ... , B12 deficiency ... Reticulocytosis, MDS ... Matthew Ho, MD ... #Differential #
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... ) - Differential ... (>100 fL) • B12 ... #MCV #Classification ... #Differential #
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... Reticulocytes, MCV ... • B12/Folate ... Deficiency • Aplastic ... #Classification
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
812, Folate ... Deficiency • ... MDS+ • Hypothyroid ... #differential # ... algorithm #hematology #workup
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Megaloblastic: Vitamin B12 ... deficiency, Folate ... deficiency • ... Myelodysplastic syndrome ... #differential #
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
, GATA2 deficiency ... , CTLA4 deficiency ... - Parvovirus B19 ... (MDS) (normal or ... Hypocellular/Hypoplastic MDS
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
Whipple, vitamin deficiency ... - Progressive amnesia ... Aphaso-apraxo-agnosia syndrome ... MNCD #Dementia #Differential ... #Subtypes #Classification
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Nutritional: vitamin B12 ... or folic acid deficiency ... Workup: • Complete ... blood count with differential
FAT RBC Mnemonic for Causes of Macrocytic Anemia
(MCV > 100)

F - Folate (Fetus) and B12 Deficiency
(MCV > 100) ... Folate (Fetus) and B12 ... Deficiency - Impairs ... Marrow Disorders (MDS ... #Differential #