22 results
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Hypoproliferative Macrocytic ... Anemia812 ... , Folate Deficiency ... #Anemia #differential ... algorithm #hematology #workup
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... • Drugs Oval Macrocytes ... • Dietary Deficiency ... - Low Serum B12 ... and Folate Deficiency
Causes of Vitamin B12 Deficiency - Cobalamin
Decreased Intake
Pancreas: Insufficiency
Intestine: SIBO, Celiac disease, IBD, Lymphoma, Amyloidosis, Resection,
Causes of Vitamin B12 ... Deficiency - Cobalamin ... Stomach: Pernicious anemia ... #Deficiency #Cobalamin ... #differential #
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Approach - MCV) Low ... " • Iron deficiency ... MCV - >96fL - "Macrocytic ... Megaloblastic: Vitamin B12 ... morphologic #mcv #differential
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential ... inflammation) • Iron deficiency ... Infections Macrocytic ... , B12 deficiency ... MCV #Algorithm #Differential
Causes of Low Vitamin B12 Levels
Low vitamin B12 intake - Vegetarianism, chronic alcoholism and older people
Autoimmune
B12 Levels Low ... vitamin B12 intake ... Autoimmune - Pernicious anaemia ... #low #cobalamin ... #differential #
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
95 (or 100) is macrocytic ... (EPO), iron or B12 ... Low in bone marrow ... Algorithm #Diagnosis #Workup ... #Macrocytic
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
Vitamin B12 (Cobalamin ... ) Deficiency Etiology ... cobalamin. ... : • Worsening macrocytic ... #Cobalamin #Deficiency
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
evaluation of macrocytic ... of the initial work-up ... deficiency is present ... deficiency. ... #Macrocytosis #Macrocytic
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Diagnosis Algorithm Low ... (>100 fL) • B12 ... #MCV #Classification ... #Differential #