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diagnosis hematology management atlas bariatric bloodcell bypass causes cobalamin deficiencies gastric mcv mds microscopy morphologic morphology myelitis myelodysplasia myelodysplastic neurology
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
and Vitamin Deficiency ... • Thiamine B1 ... B12 - Anaemia, ... #Deficiency #differential ... signs #symptoms #nutrition
Micronutrient Deficiencies After Gastric Bypass Fat-Soluble Vitamins: • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
cardiomyopathy) • Folate - Macrocytic ... anemia • Vitamin ... B12 - Macrocytic ... #nutrition #table ... #differential #
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
" • Iron deficiency ... MCV - >96fL - "Macrocytic ... Megaloblastic: Vitamin ... B12 deficiency, ... morphologic #mcv #differential
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC) Morphology Microcytic ... RBC: Pyridoxine deficiency ... (sometimes) Macrocytic ... RBC: Vitamin B12 ... RBC #Morphology #differential
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Pancytopenia - Differential ... • Fanconi’s anemia ... Antibody-mediated hemolysis Nutritional ... consumption • Vitamin ... B12 • Folate deficiency
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
Vitamin B12 (Cobalamin ... ) Deficiency Etiology ... : • Worsening macrocytic ... @taleanski #Vitamin ... #management #nutrition
Etiologies of Vitamin B12 Deficiency • Inadequate intake - Rare but seen in very strict vegans
B12 Deficiency ... B12 deficiency. ... B12 deficiency. ... autoantibodies (pernicious anemia ... #differential #
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
common cytopenia: Macrocytic ... Platelet Disorders • Nutritional ... : vitamin B12 or ... folic acid deficiency ... blood count with differential
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
B12 and copper ... antibodies • Nutritional ... Deficiency: - ... Vitamin B12, E, ... management #neurology #differential
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