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diagnosis hematology classification elevation acidosis algorithm dm2 false hba1c hgba1c increase laboratory lactate lactic mania manic mcv mds morphologic myelodysplasia
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach ... to Anemia - Differential ... Deficiency • ... B12/Folate Deficiency ... Diagnosis #Algorithm #Causes
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... RBC turnover • Iron ... , B-12, or folate ... deficiency • ... #DM2 #Differential
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
(Morphological Approach ... Microcytic" • Iron ... Megaloblastic: Vitamin B12 ... morphologic #mcv #differential ... #diagnosis #causes
Medical Conditions Causing Mania or Mania-Like Episodes: Pathogenesis • Bipolar Disorder -> Combination of individual, genetic,
demyelination alters ... deficiency -> Lack ... of B12 as a cofactor ... Manic #Secondary #Causes ... #Differential #
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... malignancy, or thiamine deficiency ... muscle use • Decreased ... 30mmHg) - Severe anemia ... effect - Thiamine deficiency
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Nutritional: vitamin B12 ... or folic acid deficiency ... treatments • Copper deficiency ... rings of excess iron ... blood count with differential
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