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diagnosis hematology algorithm aafp macrocytosis management mcv anosmia atlas bariatric bloodcell bypass deficiencies dysfunction elevatedmcv fatigue folicacid gastric homocysteine hyposmia
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Anemia • 812 ... , Folate Deficiency ... • MDS+ • Hypothyroid ... #Anemia #differential ... algorithm #hematology #workup
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential ... Infections Macrocytic ... Megaloblastic: Folate ... deficiency, B12 ... Reticulocytosis, MDS
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Volume (MCV) - Differential ... • Drugs Oval Macrocytes ... • Dietary Deficiency ... and Folate Deficiency
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
evaluation of macrocytic ... the most likely cause ... recovery also causes ... deficiency. ... #Folate #FolicAcid
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
MCV - >96fL - "Macrocytic ... Megaloblastic: Vitamin B12 ... deficiency, Folate ... morphologic #mcv #differential ... #diagnosis #causes
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
(sometimes) Macrocytic ... RBC: Vitamin B12 ... or Folate deficiency ... Liver Disease, MDS ... RBC #Morphology #differential
Micronutrient Deficiencies After Gastric Bypass Fat-Soluble Vitamins: • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
cardiomyopathy) • Folate ... - Macrocytic anemia ... • Vitamin B12 ... - Macrocytic anemia ... nutrition #table #differential
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
Crohn's > UC Anemia ... • Supplement folate ... Receptor (sTfR) to differentiate ... restricted diet/deficiency ... /other causes •
Renal Replacement Therapy (RRT) - ICU One Pager Summary Indications (AIEOU): • A: Acidosis (usually severe metabolic)
Dialyzer is rigid case ... (Sustained low efficiency ... daily dialysis): ~12 ... by Nick Mark MD ... #managment #nephrology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... common cytopenia: Macrocytic ... Nutritional: vitamin B12 ... Workup: • Complete ... blood count with differential
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