7 results
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
formerly known as ... crisis • Severe B12 ... deficiency • Mechanical ... macroangiopathic hemolytic anemia ... diagnosis #hematology
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Algorithm - Iron deficiency ... disease - Vitamin B12 ... Underproduction #Algorithm #hematology ... #diagnosis #differential ... #workup
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
812, Folate ... Deficiency • ... #differential # ... diagnosis #algorithm #hematology ... #workup
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC: Pyridoxine deficiency ... Macrocytic RBC: Vitamin B12 ... Schistocyte: Microangiopathic ... RBC #Morphology #differential ... #diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Hemoglobin H disease • Schistocytes ... Diagnosis #Algorithm #workup ... #hematology #testing
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
Haptoglobin - Low as ... smear - Shows schistocytes ... WBC count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Nutritional: vitamin B12 ... Workup: • Complete ... blood count with differential ... Syndromes #diagnosis #hematology