11 results
Lactic Acidosis - Classification and Differential Diagnosis
Type A Lactic Acidosis: Inadequate Oxygen Delivery
 • Anaerobic muscular
- Classification ... delivery: Hypoxemia, Anemia ... Type B Lactic Acidosis ... syndrome, Thiamine deficiency ... #TypeB #lactate
Lactic Acidosis - Overview and Pathophysiology
Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
Pathophysiology Lactic acid ... Lactate is the conjugate ... as an arterial lactate ... #types #differential ... pathophysiology #classification
Metabolic Acidosis with Anion Gap - KILU Mnemonic

K - Ketoacidosis
	• DKA
		- With normal glucose, ask if
Metabolic Acidosis ... Anion Gap - KILU Mnemonic ... inhibitors and SGLT2 deficiency ... linezolid U - Uremia ... #diagnosis #differential
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Differential ... 30mmHg) - Severe anemia ... effect - Thiamine deficiency ... #Elevation #Differential ... #typeb #classification
Types of Anion Gap Acidosis - AGAPS KIL U - Mnemonic
Ketoacidosis: Alcoholic Ketoacidosis, Starvation Ketoacidosis, Starvation
Types of Anion Gap ... KIL U - Mnemonic ... or IV Lorazepam Uremia ... other organic acids ... #differential #
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
- Differential Diagnosis ... Framework Type ... Shock, Severe Anemia ... PRIS), Valproic Acid ... #Differential #
Type B Lactic Acidosis
Elevated lactic acid when no systemic hypoperfusion is apparent
Causes:
 • Drugs (metformin, linezolid,
Type B Lactic Acidosis ... Elevated lactic acid ... to clear) • D-lactate ... metabolism • Thiamine deficiency ... #differential #
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Acid Base Disorders ... Differentials? ... ) D D-lactate ... Renal failure (uremia ... ABG #bloodgas #Acid
Etiologies of Vitamin B12 Deficiency
 • Inadequate intake - Rare but seen in very strict vegans
lack of stomach acid ... deficiency. ... autoantibodies (pernicious anemia ... #VitaminB12 #deficiency ... #differential #
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Nutritional: vitamin B12 ... or folic acid deficiency ... treatments • Copper deficiency ... One blood cell type ... blood count with differential