12 results
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Corpuscular Volume (MCV ... • Dietary Deficiency ... - Low Serum B12 ... - Abnormal Liver
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Corpuscular Volume (MCV ... Low Mean Corpuscular ... Chronic Disease Normal ... (>100 fL) • B12
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
) Low MCV - <80fL ... some patients) Normal ... Megaloblastic: Vitamin B12 ... deficiency • ... differential #diagnosis #causes
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... Reticulocytes, MCV ... RBC Production - Normal ... • B12/Folate ... #Causes #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Causes of Anemia ... with Low Mean Corpuscular ... Differential Diagnosis Algorithm ... RBC>13 • Iron Deficiency ... Malabsorption, Dietary Deficiency
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... and petechiae Causes ... , GATA2 deficiency ... , CTLA4 deficiency ... may result from low
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... anemia (MCV 80- ... well as varying clinical ... These causes could ... Normal range11.5
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... • Pernicious anemia ... /B12 deficiency ... respiratory failure • Neurologic ... Phosphatase: • Other causes
Hoffman's sign. Even in this specific case, accompanied by a clonus outline (rhythmic contractions). The median
this specific case ... patient to relax the hand ... Reflex #Positive #Abnormal ... #clinical #video ... #neurology #PhysicalExam
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Diagnosis = clinical ... 50 in GCA, but normal ... variably: On one hand ... systemic complaints- anemia