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differential management spinal spinalcord algorithm alkaline als amyotrophic cobalamin disorders generalized hepatology hyophosphatasia lateral lesions low myelitis neuromuscular phosphatase sclerosis
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... • Thiamine B1 ... #differential #diagnosis ... #signs #symptoms ... #nutrition
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Weakness • Spinal ... Cord: Demyelinating ... Motor Nerves: ALS ... : Acid maltase deficiency ... #diagnosis #neurology
Generalized Weakness - Differential Diagnosis Framework "l feel weak": • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis •
Generalized Weakness ... : CHF, valves, COPD ... ILD, OSA, pHTN, Anemia ... Polyneuropathy, ALS ... #causes #neurology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... Most cases diagnosed ... • Pernicious anemia ... /B12 deficiency ... ) - Waddling gait
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
neurological lesion: Clinical ... • Symptoms and signs ... of injury • Gait ... Causes: 1. ... myelopathy - Vit B12
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... HIV) - Vitamin B12 ... , Copper deficiency ... #differential #diagnosis ... #neurology
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... intrinsic factor, IF) Clinical ... parasthesias, gait ... #nutrition
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... • Bilateral signs ... antibodies • Nutritional ... Deficiency: - ... #management #neurology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of the clinical ... multiple spinal cord ... - Causes progressive ... weakness in the ... Lateral #Sclerosis #neurology
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