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diagnosis differential management cord spinalcord algorithm alkaline alp aplastic associated classification cobalamin crrt dementia disorder disorders elevation hand hematology hepatology
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... intrinsic factor, IF) Clinical ... parasthesias, gait ... , alcohol use, symptoms
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
• Pernicious anemia ... /B12 deficiency ... mineralization Symptoms ... ) - Waddling gait ... Phosphatase: • Other causes
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
neurological lesion: Clinical ... of injury • Gait ... Cord Causes: 1 ... myelopathy - Vit B12 ... disorders #diagnosis #neurology
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... Causes of spinal ... HIV) - Vitamin B12 ... , Copper deficiency ... Lower motor neuron symptoms
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
malignancy, or thiamine deficiency ... LV failure - Low ... 30mmHg) - Severe anemia ... Nonhypoxic • Type B1 ... effect - Thiamine deficiency
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... , GATA2 deficiency ... • Improve the symptoms ... may result from low
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... Bilateral signs and/or symptoms ... Check Vitamin B12 ... • Nutritional Deficiency ... diagnosis #management #neurology
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
ARVs can have low ... • Depressive symptoms ... dysfunction like gait ... disorder #dementia #AIDS ... #Neurology
Renal Replacement Therapy (RRT) - ICU One Pager Summary Indications (AIEOU): • A: Acidosis (usually severe metabolic)
(AIEOU): • A: Acidosis ... Dialyzer is rigid case ... SLEDD (Sustained low ... efficiency daily ... dialysis): ~12
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
treatment of HIV/AIDS ... be present: • AIDS ... with low pretreatment ... initiation Clinical ... blindness, or gait
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