11 results
Wernicke Encephalopathy - Acute Thiamine (B1) Deficiency 
Clinical Diagnosis - Caine Criteria (2 out of 4):
(B1) Deficiency ... Clinical Diagnosis ... dysfunction and gait ... #B1 #Deficiency ... #neurology
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
(Thiamine) Deficiency ... Management Diagnosis ... dysfunction (e.g. gait ... #Thiamine #Deficiency ... #Diagnosis #Management
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency

Wernicke's encephalopathy is a neurological condition due to longstanding
(vitamin B1) deficiency ... ataxia (broad-based gait ... thiamine #deficiency ... Korsakoff #Syndrome #diagnosis ... #comparison #neurology
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
fatigue despite clinical ... Crohn's > UC Anemia ... restricted diet/deficiency ... /other causes • ... #diagnosis #management
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... intrinsic factor, IF) Clinical ... parasthesias, gait ... #diagnosis #management
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Most cases diagnosed ... • Pernicious anemia ... /B12 deficiency ... ) - Waddling gait
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... and petechiae Causes ... , GATA2 deficiency ... oncology #hematology #diagnosis ... #management
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
malignancy, or thiamine ... deficiency are ... 30mmHg) - Severe anemia ... Warburg effect - Thiamine ... deficiency -
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
neurological lesion: Clinical ... of injury • Gait ... myelopathy - Vit B12 ... #neurology #differential ... #algorithm
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
and Management ... and pernicious anemia ... Clinical Manifestations ... • Wide based gait ... #neurology