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diagnosis management algorithm spinalcord syndrome weakness alkaline alp als amyotrophic behcet cobalamin disease disorders fatigue generalized hepatology hyophosphatasia lateral lesions
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Spinal Cord Disorders ... lesion: Clinical ... of injury • Gait ... Cord Causes: 1 ... myelopathy - Vit B12
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
cord - Spinal Cord ... Causes of spinal ... HIV) - Vitamin B12 ... , Copper deficiency ... #lesions #differential
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
fatigue despite clinical ... Receptor (sTfR) to differentiate ... restricted diet/deficiency ... symptoms even if ... /other causes •
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... intrinsic factor, IF) Clinical ... diarrhea related to IBD ... parasthesias, gait
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
Inhibited Pathway caused ... cord, which is ... deficiency. ... The classic clinical ... of pernicious anemia
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Weakness • Spinal ... Cord: Demyelinating ... : Acid maltase deficiency ... #differential # ... diagnosis #neurology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... Bilateral signs and/or symptoms ... • Infectious causes ... • Nutritional Deficiency ... #differential
Generalized Weakness - Differential Diagnosis Framework "l feel weak": • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis •
: CHF, valves, COPD ... , ILD, OSA, pHTN ... , Anemia • Psych ... #Diagnosis #causes ... #neurology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... • Pernicious anemia ... /B12 deficiency ... mineralization Symptoms ... ) - Waddling gait
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
and pernicious anemia ... the brain and spinal ... cord. ... Clinical Manifestations ... • Wide based gait
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