14 results
Wernicke Encephalopathy - Acute Thiamine (B1) Deficiency 
Clinical Diagnosis - Caine Criteria (2 out of 4):
Acute Thiamine (B1 ... ) Deficiency Clinical ... dysfunction and gait ... Encephalopathy #Thiamine #B1 ... #Deficiency #diagnosis
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency

Wernicke's encephalopathy is a neurological condition due to longstanding
thiamine (vitamin B1 ... ataxia (broad-based gait ... #vitaminB1 #B1 # ... #diagnosis #comparison ... #neurology
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
Encephalopathy - Acute B1 ... dysfunction (e.g. gait ... (chronic B1 deficiency ... Encephalopathy #B1 ... #neurology #nutrition
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • Aplastic ... Anemia • Toxic ... Megakaryopoiesis • B12 ... Non-lmmune: • HELLP Syndrome
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... • Thiamine B1 ... Wernicke-Korsakoff syndrome ... gestation • Vitamin B12 ... #differential #diagnosis
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Anemia Clinical ... and petechiae Causes ... #hematology #diagnosis
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... intrinsic factor, IF) Clinical ... parasthesias, gait ... #Cobalamin #Deficiency
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Most cases diagnosed ... • Pernicious anemia ... /B12 deficiency ... ) - Waddling gait
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
AnemiaAplastic ... Nutritional: vitamin B12 ... or folic acid deficiency ... treatments • Copper deficiency ... #diagnosis #hematology
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... HIV) - Vitamin B12 ... , Copper deficiency ... #differential #diagnosis ... #neurology