15 results
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
Nutritional: DiabetesB12 deficiency ... , Uremia/ESRD, Hypothyroidism ... Inflammatory/AI: CIDP, Guillain-Barre ... #differential #diagnosis ... #causes #neurology
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Reflex Testing - ... Causes of Hyporeflexia ... Guillain-Barré syndrome ... #differential #diagnosis ... #table #neurology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Poliomyelitis, Guillain-Barre ... : Acid maltase deficiency ... #differential #diagnosis ... #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... than females Guillain-Barre ... bulbar muscles Guillain-Barre ... • Areflexia Guillain-Barre ... #treatment #neurology
Wernicke Encephalopathy - Acute Thiamine (B1) Deficiency 
Clinical Diagnosis - Caine Criteria (2 out of 4):
) Deficiency Clinical ... Diagnosis - Caine ... dysfunction and gait ... #Deficiency #diagnosis ... #criteria #neurology
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency

Wernicke's encephalopathy is a neurological condition due to longstanding
ataxia (broad-based gait ... and retrograde amnesia ... #vitaminB1 #B1 # ... Korsakoff #Syndrome #diagnosis ... #comparison #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... transplantation CLINICAL ... depressed deep tendon reflexes ... #neurology
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... intrinsic factor, IF) Clinical ... parasthesias, gait ... #Cobalamin #Deficiency
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... • Pernicious anemia ... /B12 deficiency ... ) - Waddling gait ... Phosphatase: • Other causes
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... and petechiae Causes ... , GATA2 deficiency ... CMV) • Epstein-Barr ... oncology #hematology #diagnosis