25 results
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
and Management ... treatment can improve symptoms ... development of Korsakoff syndrome ... (chronic B1 deficiency ... #Management #neurology
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency

Wernicke's encephalopathy is a neurological condition due to longstanding
vs Korsakoff Syndrome ... - Thiamine Deficiency ... and retrograde amnesia ... #vitaminB1 #B1 # ... diagnosis #comparison #neurology
Korsakoff Syndrome
Clinical Findings:
 • Confabulation: Usually initial phase of the disease
 • Anterograde amnesia: Memory impairment
Clinical Findings ... • Anterograde amnesia ... presentation of Thiamine deficiency ... untreated Wernicke Encephalopathy ... #neurology #diagnosis
Wernicke Encephalopathy - Acute Thiamine (B1) Deficiency 
Clinical Diagnosis - Caine Criteria (2 out of 4):
Wernicke Encephalopathy ... Acute Thiamine (B1 ... ) Deficiency Clinical ... #Thiamine #B1 # ... #criteria #neurology
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Vitamins and Vitamin Deficiency ... Wernicke-Korsakoff syndrome ... gestation • Vitamin B12 ... diagnosis #signs #symptoms
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... , GATA2 deficiency ... , CTLA4 deficiency ... • Improve the symptoms ... hematology #diagnosis #management
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... intrinsic factor, IF) Clinical ... to manifest its symptoms ... , alcohol use, symptoms ... #diagnosis #management
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
fatigue despite clinical ... Crohn's > UC Anemia ... restricted diet/deficiency ... symptoms even if ... Algorithm #diagnosis #management
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... Other brainstem syndromes ... facial numbness), Encephalopathy ... Manifestations #diagnosis #neurology ... #symptoms #signs
Hyponatremia Correction
1. Indications for Hypertonic Saline: seizure, coma, focal findings
   - typically occurs with
100-110 - Symptoms ... not to exceed 10-12 ... Demyelination Syndrome ... Correction #goal #rate #management ... #nephrology