15 results
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
e.g AEIOU ) or anuria ... require urgent nephrology ... creatinine (in 12 ... KidneyInjury #simplified #workup ... #diagnosis #nephrology
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
neurocognitive disorders ... 1) Clinical ... Whipple, vitamin deficiency ... Alzheimer - 1st cause ... - Progressive amnesia
Causes of Dementia / Cognitive Impairment - Differential Diagnosis Algorithm

Affecting Multiple Domains
 • Depression
 • Delirium
Decline
Causes of Dementia ... Subdural Hematoma • B12 ... deficiency • ... Paraneoplastic disorder ... CognitiveImpairment #Dementia #Neurology
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... dysfunction, and/or disorders ... intrinsic factor, IF) Clinical ... #Cobalamin #Deficiency
How do you work up an ischemic CVA?
A) Initial Evaluation
 • ABCs
 • IV access, monitor
How do you work ... angiography • +/- Vit B12 ... #CVA #stroke #workup ... #diagnosis #checklist ... #neurology
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
ILD, OSA, pHTN, Anemia ... Rhabdomyolysis, Critical ... Polyneuropathy, ALS), NMJ disorder ... Differential #Diagnosis #causes ... #neurology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... • Pernicious anemia ... /B12 deficiency ... respiratory failure • Neurologic ... Phosphatase: • Other causes
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Nutritional: vitamin B12 ... or folic acid deficiency ... Workup: • Complete
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Non-neuromuscular disorder ... endocrine: Vitamin B12 ... deficiency • ... dystrophies Work ... Differential #Diagnosis #neurology
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Acid Base Disorders ... HCO3)} Normal = 12 ... Renal failure (uremia ... #AcidBase #disorders ... Diagnosis #Summary #Nephrology