Causes of Dementia / Cognitive Impairment - Differential Diagnosis Algorithm
Affecting Multiple Domains
• Depression
• Delirium
Decline in Instrumental Activities of Daily Living
• Amnestic Mild Cognitive Impairment
• Non-Amnestic Mild Cognitive Impairment
Subcortical Dementia - Treatable Causes
• Normal Pressure Hydrocephalus
• Chronic Meningitis
• Chronic Drug Abuse
• Tumor
• Subdural Hematoma
• B12 deficiency
• Hypothyroidism
• Hypoglycemia
Subcortical Dementia - Early Extrapyramidal Features
• Parkinson's Disease with Dementia
• Huntington's Disease
Subcortical Dementia - Rapidly Progressive
• Creutzfeldt-Jakob Disease
• Paraneoplastic disorder
Cortical Dementias:
• Early Language and Behavioral Dysfunction - Fronto-temporal Dementia
• Abrupt Onset, Stepwise Progression - Vascular Dementia
• Early Impairment of Recent Memory - Alzheimer's Dementia
• Early Extrapyramidal Features -Dementia with Lewy
Bodies
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