18 results
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
B12/Folate ... Deficiency • Aplastic ... • RBC Membrane Disorder ... #Classification ... Diagnosis #Algorithm #Causes
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
neurocognitive disorders ... 1) Clinical ... Whipple, vitamin deficiency ... - Progressive amnesia ... Differential #Subtypes #Classification
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
e.g AEIOU ) or anuria ... require urgent nephrology ... creatinine (in 12 ... KidneyInjury #simplified #workup ... #diagnosis #nephrology
Causes of Dementia / Cognitive Impairment - Differential Diagnosis Algorithm

Affecting Multiple Domains
 • Depression
 • Delirium
Decline
Causes of Dementia ... Subdural Hematoma • B12 ... deficiency • ... Paraneoplastic disorder ... CognitiveImpairment #Dementia #Neurology
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... dysfunction, and/or disorders ... intrinsic factor, IF) Clinical ... #Cobalamin #Deficiency
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
ILD, OSA, pHTN, Anemia ... Rhabdomyolysis, Critical ... Polyneuropathy, ALS), NMJ disorder ... Differential #Diagnosis #causes ... #neurology
Generalized Seizures and Pseudoseizures
Generalized seizures "are conceptualized as originating as some point within, and rapidly engaging,
general seizure caused ... and metabolic causes ... sedative drugs, uremia ... Pseudoseizures #GrandMal #Classification ... #Diagnosis #Neurology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... • Pernicious anemia ... /B12 deficiency ... respiratory failure • Neurologic ... Phosphatase: • Other causes
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Nutritional: vitamin B12 ... or folic acid deficiency ... Workup: • Complete
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Non-neuromuscular disorder ... endocrine: Vitamin B12 ... deficiency • ... dystrophies Work ... Differential #Diagnosis #neurology