18 results
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Hypoproliferative Macrocytic ... Anemia812 ... , Folate Deficiency ... #Anemia #differential ... algorithm #hematology #workup
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... • Pernicious Anemia ... • Small Bowel Disorder ... • Pernicious Anemia ... #Anemia #Macrocytosis
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
anemia, Chronic ... (sometimes) Macrocytic ... RBC: Vitamin B12 ... Echinocyte): Artifact, Uremia ... Unstable hemoglobin disorders
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Anemia - Underproduction ... anemia - Anemia ... disease - Vitamin B12 ... Probable bone marrow disorder ... #differential #workup
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... (EPO), iron or B12 ... (BM) ablative disorders ... for degree of anemia ... thecurbsiders podcast #Anemia
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
evaluation of macrocytic ... anemia. ... elevated, but anemia ... megaloblastic anemia ... #Anemia #VitaminB12
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
anemia (MCV<80 ... MCV 80-100 fl) & macrocytic ... anemia (MCV>100 ... well as varying clinical ... that involves disorders
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
autoantibodies (pernicious anemia ... : • Worsening macrocytic ... anemia, yellow ... wt loss • If anemia ... - CBC, PBS - anemia
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
ILD, OSA, pHTN, Anemia ... Rhabdomyolysis, Critical ... Polyneuropathy, ALS), NMJ disorder ... Diagnosis #causes #neurology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
blood cell count (anemia ... anemia DDX: ... • Aplastic Anemia ... Megaloblastic Anemia ... Myelophthisic Anemia