15 results
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Anemia - Underproduction ... anemia - Anemia ... disease - Vitamin B12 ... Probable bone marrow disorder ... #differential #workup
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Vitamins and Vitamin Deficiency ... - Coagulation disorder ... gestation • Vitamin B12 ... signs #symptoms #nutrition
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
dysfunction, and/or disorders ... autoantibodies (pernicious anemia ... Worsening macrocytic anemia ... wt loss • If anemia ... - CBC, PBS - anemia
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
• Metabolic / Nutritional ... : DiabetesB12 deficiency ... , Uremia/ESRD, Hypothyroidism ... diagnosis #causes #neurology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Scurvy (Vitamin C Deficiency ... persons with poor nutrition ... Clinical Presentation ... breath, wasting, anemia ... Loss of teeth Anemia
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
ILD, OSA, pHTN, Anemia ... Rhabdomyolysis, Critical ... Polyneuropathy, ALS), NMJ disorder ... Diagnosis #causes #neurology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
blood cell count (anemia ... • Aplastic Anemia ... Megaloblastic Anemia ... Myelophthisic Anemia ... dyserythropoietic anemia
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Non-neuromuscular disorder ... endocrine: Vitamin B12 ... deficiency • ... dystrophies Work ... Differential #Diagnosis #neurology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... • Vitamin C deficiency ... • Pernicious anemia ... /B12 deficiency ... respiratory failure • Neurologic
Renal Replacement Therapy (RRT) - ICU One Pager Summary
Indications (AIEOU):
 • A: Acidosis (usually severe metabolic)
U: Symptomatic Uremia ... daily dialysis): ~12 ... Corrects uremia, ... Gently corrects uremia ... RRT #managment #nephrology