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differential hematology causes algorithm management classification nephrology testing gastroenterology laboratory macrocytic mcv oncology pancytopenia pathophysiology cardiology dementia dermatology elevation evaluation
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
- Iron deficiency ... chronic kidney disease ... - Vitamin B12 ... Probable bone marrow disorder ... #differential #workup
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... : IBD, Chronic disease ... metabolism disorders ... #differential #diagnosis ... #anemia #nutrition
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
deficiency anemia ... Macrocytic RBC: Vitamin B12 ... Unstable hemoglobin disorders ... deficiency anemia ... #differential #diagnosis
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... MCH, MCHC, Serum Iron ... Deficiency • ... B12/Folate Deficiency ... Disease • Marrow
Gastrointestinal Evaluation of Iron Deficiency Anemia In patients with anemia, diagnose iron deficiency if: • Ferritin <
Deficiency Anemia ... , diagnose iron ... Test for celiac disease ... #Deficiency #Anemia ... Gastrointestinal #Evaluation #workup
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... - Coagulation disorder ... gestation • Vitamin B12 ... #differential #diagnosis ... signs #symptoms #nutrition
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
- Differential Diagnosis ... Volume (<80 fL) • Iron ... Deficiency • ... (>100 fL) • B12 ... #Differential #Diagnosis
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Loss (without anaemia ... IBD, cancer) #Iron ... #diagnosis #causes ... #nutrition
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
• 812, Folate ... Deficiency • ... Hypothyroid • Liver Disease ... #differential #diagnosis ... algorithm #hematology #workup
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential Diagnosis ... inflammation) • Iron ... , B12 deficiency ... Non-megaloblastic: Liver disease ... #Differential #Diagnosis
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