24 results
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Hypoproliferative Macrocytic ... Anemia812 ... , Folate Deficiency ... #Anemia #differential ... algorithm #hematology #workup
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
evaluation of macrocytic ... the most likely cause ... recovery also causes ... of the initial work-up ... deficiency.
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... • Drugs Oval Macrocytes ... • Dietary Deficiency ... and Folate Deficiency ... Liver Disease #Macrocytic
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
" • Iron deficiency ... MCV - >96fL - "Macrocytic ... Megaloblastic: Vitamin B12 ... deficiency • ... differential #diagnosis #causes
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Vitamins and Vitamin Deficiency ... gestation • Vitamin B12 ... #Vitamins #Deficiency ... signs #symptoms #nutrition
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Causes of Neutropenia ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional ... deficiency: • ... B12/folate/combined
Micronutrient Deficiencies After Gastric Bypass
Fat-Soluble Vitamins:
 • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
• Thiamine - Nausea ... cardiomyopathy) • Folate - Macrocytic ... anemia • Vitamin ... B12 - Macrocytic ... Bypass #vitamin #nutrition
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... intrinsic factor, IF) Clinical ... : • Worsening macrocytic ... diagnosis #management #nutrition
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
• Metabolic / Nutritional ... : DiabetesB12 deficiency ... , Uremia/ESRD, Hypothyroidism ... differential #diagnosis #causes ... #neurology
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
corpuscular volume into microcytic ... MCV 80-100 fl) & macrocytic ... hemoglobin of less than 12 ... well as varying clinical ... These causes could