26 results
Methylmalonic Acid and Homocysteine Levels in Vitamin B12 and Folate Deficiency
 • B12 Deficiency: MMA elevated,
Levels in Vitamin B12 ... and Folate Deficiency ... • B12 Deficiency ... #B12 #MMA #folate ... #diagnosis #hematology
Diagnosing Vitamin B12 and/or Folate Deficiency

It turns out that simply measuring serum levels of B12 or
and/or Folate Deficiency ... conversion of homocysteine ... lead to elevated homocysteine ... Both homocysteine ... #Nutrition #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
inflammation) • Iron ... deficiency • ... Megaloblastic: Folate ... deficiency, B12 ... Differential #Diagnosis #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Microcytic" • Iron ... deficiency • ... Megaloblastic: Vitamin B12 ... deficiency, Folate ... diagnosis #causes #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Reticulocytes, MCV ... Iron, Ferritin, ... Reticulocytes • Iron ... Deficiency • ... B12/Folate Deficiency
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... Volume (<80 fL) • Iron ... (>100 fL) • B12 ... Folate Deficiency ... #MCV #Classification
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Algorithm - Iron ... deficiency anemia ... disease - Vitamin B12 ... and/or folate deficiency ... Underproduction #Algorithm #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Corpuscular Volume (MCV ... Neutrophils - Low RBC Folate ... • Dietary Deficiency ... and Folate Deficiency ... Algorithm #Causes #Hematology
Iron Deficiency Anemia (IDA)
Tests:
 • MCV/RBC - RBC ↓ in proportion to the ↓ in hemoglobin
Iron Deficiency ... Anemia (IDA) Tests ... : • MCV/RBC - ... #Deficiency #Anemia ... Fe #diagnosis #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Causes of Anemia ... Corpuscular Volume (MCV ... Deficiency (Eg ... Malabsorption, Dietary Deficiency ... Algorithm #Causes #Hematology