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diagnosis hematology differential algorithm causes management aplastic approach b1 comparison encephalopathy erythematosus korsakoff mcv mds monoclonal myelodysplasia myelodysplastic nephritis nephrology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
(>100 fL) • B12 ... Deficiency • ... Folate Deficiency ... #MCV #Classification ... Algorithm #Causes #Hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Diseases: • GATA2 deficiency ... • Fanconi’s anemia ... Diseases: • Systemic lupus ... consumption • Vitamin B12 ... • Folate deficiency
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Reticulocytes • Iron Deficiency ... • B12/Folate ... Deficiency • Aplastic ... #Classification ... Algorithm #Causes #Hematology
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency Wernicke's encephalopathy is a neurological condition due to longstanding
thiamine (vitamin B1 ... ) deficiency, commonly ... and retrograde amnesia ... #vitaminB1 #B1 # ... diagnosis #comparison #neurology
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
severity (ISN/RPS classification ... 0.5-0.7 g/g by 12 ... months Classification ... treatment #management #rheumatology ... #nephrology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
, GATA2 deficiency ... , CTLA4 deficiency ... - Parvovirus B19 ... • Parvovirus B19 ... #oncology #hematology
Etiologies of Vitamin B12 Deficiency • Inadequate intake - Rare but seen in very strict vegans
Deficiency • Inadequate ... deficiency. ... autoantibodies (pernicious anemia ... #VitaminB12 #deficiency ... differential #diagnosis #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Non-autoimmune rheumatologic ... disease • Prolidase deficiency ... lymphopenia, low PLT • Anemia ... Erythematosus #Diagnosis #Rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... (-) hemolytic anemia ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Nutritional: vitamin B12 ... or folic acid deficiency ... treatments • Copper deficiency ... Syndromes #diagnosis #hematology ... #oncology
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