13 results
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Tetanus, Transverse Myelitis ... Poliomyelitis, Guillain-Barre ... : Acid maltase deficiency ... differential #diagnosis #neurology
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
Diagnosis and Management ... dysfunction (e.g. gait ... development of Korsakoff syndrome ... (chronic B1 deficiency ... #neurology #nutrition
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Epidemiology: • 1-2 cases ... Treatment: • Plasmapheresis ... #diagnosis #management ... #treatment #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Check Vitamin B12 ... • Nutritional Deficiency ... Treatment: • ... #diagnosis #management ... #neurology #differential
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... parasthesias, gait ... Check for IF ab Treatment ... #diagnosis #management
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
- Emergency Causes ... • Transverse myelitis ... Tethered cord • Guillain-Barre ... axial T1 and T2 Treatment ... #neurology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... anemia, GATA2 deficiency ... , CTLA4 deficiency ... aplastic anemia Treatment ... hematology #diagnosis #management
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
Without treatment ... soles in 50% of cases ... tabes dorsalis, gait ... similar to those of B12 ... deficiency.
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
of injury • Gait ... Non-compressive Spinal Cord Causes ... - Transverse myelitis ... myelopathy - Vit B12 ... MCTD, Sjogren syndrome
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Prevalence: 1-2 cases ... • Wide based gait ... Treatment: • ... #treatment #neurology