12 results
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
soles in 50% of cases ... tabes dorsalis, gait ... similar to those of B12 ... Latent #Tertiary #Diagnosis ... of Infectious Diseases
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
and Management ... Prevalence: 1-2 cases ... • Wide based gait ... #Management #treatment ... #neurology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... Malnutrition • Wilson's disease ... Pernicious anemia/B12 ... respiratory failure • Neurologic ... ) - Waddling gait
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
• Diagnosis of ... irrigation • Management ... Kidney stones caused ... • Primary hyperaldosteronism ... insipidus • Primary
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Vaginal dryness • Primary ... Diagnosis: • Dry ... Hypocomplementemia • Can cause ... Cryoglobulinemia (4%-12% ... #Management
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
of injury • Gait ... myelopathy - Vit B12 ... Sarcoidosis, Behcet disease ... MCTD, Sjogren syndrome ... #neurology #differential
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
Trypanosomiasis - Diagnosis ... and Management ... caused by the protozoan ... cruzi Treatment - Primary ... #Management #Treatment
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
scalp tenderness, jaw ... with GCA or as primary ... affects the skin, neurologic ... Rash, arthritis Primary ... tract, and often causes
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
- Causes progressive ... (3) primary lateral ... Hyperreflexia, Increased Jaw ... Lateral #Sclerosis #neurology ... #diagnosis #management
Evaluation of Recurrent Falls

Core Concept:
Maintaining an upright posture requires the integrated function of multiple systems.
Disruption in
: Vertigo, imbalance ... e.g., diabetic, B12 ... range of motion, gait ... Recurrent #Falls #Diagnosis ... Evaluation #Geriatrics #Neurology