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differential rheumatology alkaline alp bariatric bypass cerebritis deficiencies erythematosus gastric hematology hemeonc hemophagocytic hepatology hlh hyophosphatasia inflammatory iris latent low
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... autoantibodies that will cause ... #neurology #rheumatology ... #management #treatment
Micronutrient Deficiencies After Gastric Bypass Fat-Soluble Vitamins: • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
oculomotor dysfunction, gait ... ataxia), Korsakoff syndrome ... anemia • Vitamin B12 ... dermatitis, decreased immune ... #differential #diagnosis
The Stages of Syphilis Primary Syphilis - The chancre lesion is the hallmark of primary syphilis.
soles in 50% of cases ... and nephrotic syndrome ... tabes dorsalis, gait ... similar to those of B12 ... Latent #Tertiary #Diagnosis
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Most cases diagnosed ... pain • loss of secondary ... membrane into the CNS ... Pernicious anemia/B12 ... ) - Waddling gait
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... scalp tenderness, jaw ... affects the skin, neurologic ... tract, and often causes ... chorioretinitis, CNS
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
activation of an immune ... that results in CNS ... Check Vitamin B12 ... • Infectious causes ... #management #neurology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Inflammatory Syndrome ... pleural effusions, CNS ... blindness, or gait ... : encephalitis secondary ... #Management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
other diseases • Secondary ... Diagnosis: • Dry ... Hypocomplementemia • Can cause ... Cryoglobulinemia (4%-12% ... #Management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... caused by uncontrolled ... activation of the immune ... STX11, STXBP2 • Secondary ... Emerging therapies: JAK
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