7 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... autoantibodies that will cause ... #neurology #rheumatology ... #management #treatment
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... other diseases • Secondary ... Syndrome Diagnosis ... Hypocomplementemia • Can cause ... #Diagnosis #Management
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
soles in 50% of cases ... and nephrotic syndrome ... tabes dorsalis, gait ... similar to those of B12 ... Latent #Tertiary #Diagnosis
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... pain • loss of secondary ... membrane into the CNS ... Pernicious anemia/B12 ... ) - Waddling gait
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
of injury • Gait ... myelopathy - Vit B12 ... sclerosis - MCTD, Sjogren ... syndrome Cord ... #neurology #differential
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... for NMO, SLE or Sjogren's ... Check Vitamin B12 ... • Infectious causes ... #management #neurology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... pleural effusions, CNS ... blindness, or gait ... : encephalitis secondary ... #Management