11 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... autoantibodies that will cause ... #CNS #neurology ... #management #treatment
Hematuria in Post-Renal Transplant Patient
Prevalence up to 12% in the postrenal transplant patient
 • Bacterial: Escherichia
Malignancies: Secondary ... (Goodpasture's syndrome ... , SLE, IgA nephropathy ... #differential #diagnosis ... #blood #urine #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... oral ulcers in 12 ... Oral aphthae : SLE ... • Arthritis: SLE ... #diagnosis #management
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
soles in 50% of cases ... and nephrotic syndrome ... tabes dorsalis, gait ... similar to those of B12 ... Latent #Tertiary #Diagnosis
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... pain • loss of secondary ... membrane into the CNS ... Pernicious anemia/B12 ... ) - Waddling gait
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
other diseases • Secondary ... overlaps with RA, SLE ... Hypocomplementemia • Can cause ... Cryoglobulinemia (4%-12% ... #Management
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
of injury • Gait ... myelopathy - Vit B12 ... Behcet disease - SLE ... MCTD, Sjogren syndrome ... #neurology #differential
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... Check Vitamin B12 ... • Infectious causes ... Disorders: - SLE ... #management #neurology
Diagnostic algorithm for differentiating vestibular neuritis from stroke in patients with AVS. This sequence of testing
is different (see ... components: targeted neurologic ... disposition, even if the cause ... CNS, Central nervous ... acute vestibular syndrome
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
diseases, such as SLE ... scalp tenderness, jaw ... affects the skin, neurologic ... tract, and often causes ... chorioretinitis, CNS