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diagnosis anthracycline cardiotoxicity chemotherapy differentiation emergencies hematology hemeonc her2 oncologic pharmacology toxicity
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... • Attempt if high ... effusions, weight gain ... #management #hematology ... #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... interventional radiology ... treat - Calcium > 12 ... (~20 %) and APL ... fever, weight gain
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity Anthracyclines cause cardiomyopathy: ✖ Reduction in left ventricular ejection fraction
Management of Anthracyclines ... ✔ If LVEF drops ... ) and initiate treatment ... Cardiotoxicity #cardiology ... #oncology #pharmacology
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