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differential management oncology anemia treatment agep algorithm aplastic bruising cancer coagulation compared comparison cryofibrinogenemia damage dic disorders disseminated erythemas exanthematous
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Diagnostic Framework ... kidney disease, Acute ... Megaloblastic: Vitamin B12 ... Myelodysplastic syndrome ... #causes #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Hemophilia - Diagnosis ... normal in mild cases ... severity Treatment - Acute ... Avoid meds that ... Management #treatment #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
malignancy (Especially acute ... organ damage Clinical ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... ecchymoses, mucosal bleeding ... and petechiae Causes ... Anemia #oncology #hematology ... #diagnosis #management
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... von Willebrand syndrome ... • Warfarin • Acute ... discern these causes ... #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... skin that are caused ... by bleeding (petechiae ... Nutritional: vitamin B12 ... #diagnosis #hematology
Moccasin-variety Tinea Pedis 70 M chronic scaly feet. Over the years: rash has itched only occasionally;
Moccasin-variety Tinea Pedis ... Diagnosis? ... dermatophytes cause ... Variety #type #clinical ... #photo #foot #dermatology
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
fires, heating pads ... children with acute ... Parvovirus B19 ... #differential #diagnosis ... #dermatology #compared
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Paradoxical spontaneous bleeding ... : • + Clinical ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... hematology
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