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management hematology algorithm cord differential disorders oncology signs spinal spinalcord syndromes anemia aplastic arteritis behcet cancer cerebritis cns cryofibrinogenemia disease
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... ecchymoses, mucosal bleeding ... • Improve the symptoms ... Anemia #oncology #hematology ... #diagnosis #management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... (Clinical Dx). ... oral ulcers in 12 ... #signs #symptoms ... #rheumatology #
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... inflammation, leading ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... HIV) - Vitamin B12 ... Lower motor neuron symptoms ... #differential #diagnosis ... #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
brain PRES Clinical ... may precede the neurologic ... Neurological symptoms ... Seizures: Treat with AEDs ... #neurology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
- Differential Diagnosis ... neurological lesion: Clinical ... myelopathy - Vit B12 ... MCTD, Sjogren syndrome ... #neurology #differential
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... unusual bruising or bleeding ... are caused by bleeding ... Nutritional: vitamin B12 ... #diagnosis #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... Paradoxical spontaneous bleeding ... : • + Clinical ... Antiphospholipid syndrome ... #rheumatology #
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Diagnosis = clinical ... in literature (NEJM ... cases (Cornelia NEJM ... them, but urgent rheumatology
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
Helpful Clinical ... Marfan syndrome, ... #History #peds ... #pediatrics #diagnosis ... #hematology #primarycare
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