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differential dermatology erythematosus lupus signs sle symptoms systemic arthritis dermatomyositis pain vasculitis algorithm antimda5 antimda5dm antinxp2 antinxp2dm autoantibodies autoimmune bleeding
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... Pain Rash ... infection Malar rash ... #differential #diagnosis ... #rheumatology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
suspicion of severe disease ... Rheumatology ... discrepancy, multiple joint ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
pain (20%) Renal disease ... ) Blood (75%): Anemia ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
69% - Malar rash ... - Neurological 12% ... - Hemolytic anemia ... autoantibodies #signs ... #differential #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Arthritis: • Joint ... arthropathy • 90% joints ... lymphopenia, low PLT • Anemia ... #Rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Arthritis Differential Diagnosis ... noninflammatory Signs ... • Parvovirus B19 ... #Differential #Diagnosis ... #MSK #rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... interphalangeal joints ... severity of the disease ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Rheumatoid Arthritis - Signs ... Musculoskeletal: Joint ... Hematological: Anemia ... #Symptoms #diagnosis ... #rheumatology
Pediatrics Sepsis Screening SIGNS OF INFECTION? • Fever (>38C) • Hypothermia (<36C) • Cough/chest pain/respiratory distress •
Pediatrics Sepsis ... diarrhea • Skin/joint ... pain/swelling/rash ... neuromuscular disease ... #peds #diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... Scleromyxedema (CNS+GI+CVS+joints ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Differential #Diagnosis
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