19 results
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
Brudzinski’s Sign ... flexion causes spinal ... an involuntary reflex ... despite severe disease ... PhysicalExam #Pediatrics #Peds
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
intervertebral disc disease ... gait, strength, reflexes ... superior iliac spine ... pathophysiology #differential ... #diagnosis #signs
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
- Differential ... and signs below ... myelopathy - Vit B12 ... Sarcoidosis, Behcet disease ... dysfunction • Abnormal reflexes
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
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Pott's Disease in ... cases Clinical Signs ... years - May have signs ... numbness, decreased reflexes ... CMC_IM #Potts #Disease
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
More Specific Signs ... abdominojugular, reflux ... Less Specific Signs ... Chest x-ray: signs ... acute HF → no signs
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Spasticity - Reflexes ... • Bilateral signs ... and/or symptoms ... Myelitis #diagnosis #management ... #neurology #differential
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of UMN and LMN signs ... Increased Jaw Jerk reflex ... of UMN and LMN signs ... both UMN and LMN signs ... EMG: LMN Signs in
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
white matter, spinal ... oral ulcers in 12 ... ) Differential Diagnosis ... Syndrome #diagnosis #management ... #signs #symptoms
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
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- Neurological 12% ... (aPL) 30-45% Differential ... autoantibodies #signs ... #symptoms #mimickers ... #differential #