11 results
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... and signs below ... myelopathy - Vit B12 ... Sarcoidosis, Behcet disease ... dysfunction • Abnormal reflexes
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
Compression/injury of Lateral ... intervertebral disc disease ... gait, strength, reflexes ... pathophysiology #differential ... #diagnosis #signs
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
Brudzinski’s Sign ... flexion causes spinal ... cord movement and ... an involuntary reflex ... despite severe disease
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
cord - Spinal Cord ... HIV) - Vitamin B12 ... Lower motor neuron symptoms ... in deep tendon reflexes ... #lesions #differential
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Spasticity - Reflexes ... Hyperreflexia develops later ... signs and/or symptoms ... Check Vitamin B12 ... management #neurology #differential
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
cord regions of ... of UMN and LMN signs ... of UMN and LMN signs ... both UMN and LMN signs ... EMG: LMN Signs in
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
More Specific Signs ... abdominojugular, reflux ... Less Specific Signs ... Chest x-ray: signs ... acute HF → no signs
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
white matter, spinal ... cord, and basal ... ) Differential Diagnosis ... diagnosis #management #signs ... #symptoms #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
- Neurological 12% ... autoantibodies #signs ... #symptoms #mimickers ... #differential # ... rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Pain - Arthritis Differential ... peripheral vs axial (spine ... noninflammatory Signs ... constitutional symptoms ... • Parvovirus B19