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diagnosis management rheumatology syndrome dermatology differential causes chronic classification hemeonc lymphocytic mds myelodysplastic photo acidosis acute algorithm allergy aplastic autoinflammatory
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... - infiltrates (anemia ... lymphocytic lymphoma (SLL ... -> Invade Skin: ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
- Summary Cancer ... non-Hodgkin lymphoma SLL ... Hepatomegaly • Skin ... • Neutropenia, anemia ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
(CLL) - Summary ... immunophenotype Clinical ... 5) Symptoms of anemia ... chemotherapy for low-risk disease ... #oncology #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management Summary ... cytopenias (usually anemia ... transformation to acute leukemia ... Allogeneic stem cell ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... Headaches • Pale skin ... virus (EBV) • Leukemia ... Treatment: ... #oncology #hematology
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
intrinsic factor, IF) Clinical ... palpitations), skin ... to IBD, celiac disease ... Check for IF ab Treatment ... diagnosis e.g. leukemia
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Somatic) Syndrome Clinical ... nose chondritis, skin ... thromboembolic disease ... Abnormalities: macrocytic anemia ... ) • giant cell
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... general feeling of ill ... , breast CA - Hematologic ... Treatment: - Systemic ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... Myeloproliferative Disease ... Nutritional: vitamin B12 ... Syndromes #diagnosis #hematology ... #oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
oral ulcers in 12 ... Oral aphthae : SLE ... tears, Ischemia, Leukemia ... • Arthritis: SLE ... Arthritis, AS Treatment
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