55 results
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Congenital Diseases ... Wiskott-Aldrich syndrome ... : • Systemic lupus ... consumption • Vitamin B12 ... Differential #Diagnosis #Hematology
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... : • Treatment: ... Skin manifestations ... #Syndrome #Treatment ... #pharmacology #rheumatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
and Primary Causes ... Cholestatic liver disease ... Myelodisplastic syndrome ... Psychiatric Disease ... #generalized #dermatology
Pyoderma Gangrenosum: Autoimmune disorder resulting in a vasculitis which causes slowly progressive 
ulceration of the skin.
vasculitis which causes ... ulceration of the skin ... a number of systemic ... Images #Clinical #Photo ... #Dermatology #SkinRash
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Associated with skin ... block • Sjogren syndrome ... polymyositis overlap syndrome ... Treatment: • ... Summary #diagnosis #rheumatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... • Pancreatic Disease ... Myelodysplastic Syndromes ... • Liver Disease ... #Hematology
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... Chain deposition disease ... antiphospholipid syndrome ... glomerulonephritis (>90%) S - Systemic ... #differential #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... - Bone marrow disease ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... highly inflammatory disease ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
associated with systemic ... disease. ... Causes: - Idiopathic ... , breast CA - Hematologic ... Treatment: - Systemic