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management diagnosis hematology hemophagocytic lymphohistiocytosis oncology syndrome anemia aplastic capsulatum classification hemeonc histoplasma histoplasmosis hivaids hodgkins idsa infections lymphoma mds
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... • Bicytopenia Treatment ... rapidly, and empiric antibiotic ... diagnosis #management #treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
) Treatment Primary ... or autoimmune disease ... , treatment of underlying ... for refractory disease ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... Lymphoma (90-95% of cases ... number of sites of disease ... Hodgkin Lymphoma Treatment ... classification #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... - β-lactam antibiotics ... - Parvovirus B19 ... aplastic anemia Treatment ... Anemia #oncology #hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome caused ... search for and treatment ... ▪ Autoimmune diseases ... Treatment Approach ... Diagnosis #Management #Hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... and lower jaw Treatment ... syndrome with acne: antibiotics ... osteoarticular and skin disease ... SAPHO #Syndrome #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Out Secondary Causes ... Myeloproliferative Disease ... Nutritional: vitamin B12 ... isoniazid) • Antibiotics ... Syndromes #diagnosis #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Cryoglobulinemia (4%-12% ... Adenocarcinoma Treatment ... lubricants • Pharmacologic ... Sjogrens #Syndrome #Rheumatology
IDSA Recommendations for Preventing and Treating Histoplasma Capsulatum Infections in HIV-AIDS Indications for Initiating Primary Prophylaxis: •
Severe Disseminated Disease ... BID for at least 12 ... IDSA #Prevention #Treatment ... #management #opportunistic ... infections #HIVAIDS #pharmacology
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